• 14.00-15.00 Registration
    15.00-15.30 Opening and Welcome
    Introduction to the XI Paul Ehrlich Euro-PhD network meeting
    J. I. Borrell (IQS School of Engineering, Universitat Ramon Llull)
    Welcome greeting from the authorities
    J. A. Rom Vice-Rector for Research and Innovation, Universitat Ramon Llull
    J. Diaz Dean of IQS School of Engineering
    S. van Calenbergh Coordinator of the Paul Ehrlich Network
    15.30-16.00 PLENARY LECTURE 1
    From enzyme inhibition to degradation: MMPs, CK and HDAC as anticancer targets
    B. de Pascual-Teresa (Professor of Organic and Pharmaceutical Chemistry, Universidad San Pablo CEU)
    President of the Spanish Society of Medicinal Chemistry (SEQT
    16.00-19.00 SESSION A
    Mini-Symposium Cancer

    16.00-16.30 Invited Lecture A
    Tackling oncogenic signaling and tumor-stroma crosstalk in aggressive B-cell lymphoma

    G. Roué (Lymphoma Translational lab, Josep Carreras Leukaemia Research Institute (IJC))
     16.30  Flash Posters in 2 min (FP-1 --> FP-12)
    17.00 Coffee break and Poster Session A
    17.45 OC-A1/ R. Listro Towards the identification of novel compounds targeting HuR ̶ RNA complexes
     18.00 OC-A2/ D. Secci Molecular hybrids as a valid strategy to modulate carbonic anhydrase isozyme inhibitors selectivity
     18.15 OC-A3/ C. Cimino Haloperidol metabolite II Valproate ester-loaded NLC as promising strategy for the treatment of Uveal Melanoma
     18.30 OC-A4/ J. Ceramella Anti-melanoma and antioxidant properties of Annona cherimola Mill. leaves extracts
    18.45 OC-A5/ R. Cosialls PET imaging of self-assembled 18F-labelled Pd2L4 metallacages for anticancer drug delivery
    19:00-21:00 Welcome Party - Cloister of the Casa d’Exercicis dels Jesuïtes
  •  9.00-9.30 PLENARY LECTURE 2
    Another awakening: Discovering a new drug for narcolepsy
    Y. Auberson
    (Executive Director in Global Discovery Chemistry, Novartis Institutes for BioMedical Research)
    Past President of the European Federation for Medicinal Chemistry and Chemical Biology (EFMC)
     9.30-12.30 SESSION B
    Mini-Symposium Anti-infectives
    9.30-10.00 Invited Lecture B
    Pan-antiviral strategies: the future ahead

    N. Izquierdo (Pathogen Immunity, Signaling and Therapeutic Applications, IRSI Caixa)
     10.00-10.30  Flash Posters in 2 min (FP-13 --> FP-32)
    10.30 Coffee break and Poster Session B
    11.15 OC-B1/ Martina Pacetti Cycloheptathiophene-3-carboxamides exert potent anti-influenza activity by interfering with polymerase PA-PB1 heterodimerization
    11:30 OC-B2/ Silvia Cammarone Resorc[4]arene-functionalized MWCNTs for the development of high selective and sensitive immunosensors
    11:45 OC-B3/ Roberta Bivacqua In silico approaches for the identification of HSV-1 Glycoprotein D inhibitors
    12:00 OC-B4/ Bárbara Nunes Antibacterial activity of ionic liquids against Staphylococcus aureus
    12:15 OC-B5/ Leticia Manén Looking for new anti-malarial drugs in the Tafenoquine Chemical Space: the Markush Dilemma.
    12.30-13.00 Keynote
    mRNA vaccines beyond Covid19
    R. Magaña Group of Materials Engineering, Gemat, IQS School of Engineering
    13.00-14.30 Lunch IQS Bar-Restaurant
    14.30-15.30 Meeting of PE Coordinators and Free Time
    15.30-18.30 SESSION C
    Mini-Symposium Other Diseases
    15.30-16.00 Invited Lecture C
    Harnessing multi-target drug discovery for neurodegeneration

    M. L. Bolognesi (Professor of Medicinal Chemistry, Università di Bologna)
     16.00 OC-C1/ Rosa Purgatorio Synthesis and biological evaluation of novel piperazine-
    containing selective BChE inhibitors as potential multimodal neuroprotective agents for
    Alzheimer's disease
    16.15 OC-C2/ Emanuela Berrino Carbon Monoxide Releasing Molecular Hybrids: Synthesis
    and Biological Evaluation of New Potent Anti-Inflammatory Agents
    16.30 Flash Posters in 2 min (FP-33 -> FP-44)
    17.00 Coffee break and Poster Session A
    17.45  OC-C3/ Rebecca Appiani Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2
    nAChR ligands with different activity profiles at the two receptor stoichiometries
    18.00 OC-C4/ Agata Zięba The 3D-QSAR studies aimed to assist the development of novel
    multi-target 5-HT2A/D2 receptor ligands
    18.15 OC-C5/ Raul Ondoño Novel MD-based drug candidates against DM1 toxic ncRNA
    18.30 Social Program - Visit To MNAC and dinner at Hotel La Florida
  • 9.30-10.30 PLENARY LECTURE 3
    Going with the Flow – The Use of Continuous Processing for Making APIs

    C. Oliver Kappe (Professor of Chemistry, University of Graz)
     10.30-11.00  Coffee break
     11.00-13.00 Presentation of the SEQT B. Pascual-Teresa
    PE MedChem Euro-PhD Label communications

    PEA-1/ A. Coricello Natural
    products in drug discovery. In Silico approaches for the detection of new hits against unexplored molecular targets

    PEA-2/ M.G. Nizi Discovery of potent and selective PARP inhibitors as valuable phar-macological tools

    PEA-3/ M. Rullo MAO B—centered multitargeting ligands against neurodegenerative disorders

    PEA-4/ M. Barreca Insight on pyrrole[1,2]oxazole derivatives in multiple lymphoma subtypes

    PEA-5/ S. Mirabile Structure- and Ligand-based optimization of fragment binding

    Awards Ceremony
    13.00-13.30 CLOSING REMARKS 
    J. I. Borrell (IQS School of Engineering, Universitat Ramon Llull)